Indications: Infections of the skin, hair, and nails (except clock spring repair the toe nail) caused by dermatophyte and or yeast (dermatophytosis, clock spring repair onychomycosis, candida perionyxixs, pityriasis versicolor, clock spring repair pityriasis capitis, Pityrosporum, clock spring repair folliculitis, chronic candidosis mucocutaneus), if the infection can not be treated topically because the surface of the skin lesions or failure clock spring repair of topical therapy. Yeast infection in the digestive cavity. Vaginal candidiasis chronic and recurrent candidiasis. At the local healing therapies less successful infection. Systemic mycosis infections clock spring repair such as systemic candidiasis, paracoccidioidomycosis, histoplasmosis, coccidioidomycosis, blastomycosis. Prophylactic treatment in patients clock spring repair decreases the body's defense mechanisms (descent, due to disease or medication), associated with increased risk of fungal infection. Ketoconazole is not penetrated well into the central nervous system. Therefore, fungal meningitis is not treated with oral ketoconazole. Contraindications: Patients with acute liver disease or chronic. Hypersensitivity to ketoconazole or any component of this medication. At the oral administration of ketoconazole should not be given together with terfenadine, astemizole, cisaprid and triazolam. Pregnant women. Composition:
Each tablet contains 200 mg ketoconazole. How Drugs Work: Ketoconazole is a synthetic derivative of imidazole-dioxolane which has a potent antimycotic activity against dermatophytes, yeasts. For example Tricophyton Sp, Epidermophyton floccosum, Sp Pityrosporum, Candida Sp. Ketoconazole works by inhibiting an enzyme "cytochrom P. 450" mushrooms, by interfering with the synthesis of ergosterol which is an essential component of fungal cell membranes. clock spring repair Dose:
Should not be used for children under the age of 2 years. Curative Treatment: clock spring repair Adult: skin infections, gastrointestinal and systemic: 1 tablet (200 mg) once daily at mealtimes. If there is no reaction to this dose, the dose was increased to 2 tablets (400 mg daily). Vaginal clock spring repair candidiasis: 2 tablets (400 mg) once daily at mealtimes. Children: Children clock spring repair weighing clock spring repair less than 15 kg: 20 mg 3 times daily at mealtimes. Children weighing 15-30 kg: 100 mg once daily at mealtimes. Children weighing clock spring repair more than 30 kg is equal to adults. clock spring repair In general, dose continued without interruption until at least 1 week after all symptoms disappeared and until the media becomes culture negative. Prophylactic treatment: 1 tablet (200 mg) once daily at mealtimes. Duration of treatment: vaginal Kondidosis 5 days. Mycosis of the skin caused by dermatoses: approximately 4 weeks. Pityriasis versicolor: 10 days. Mouth and skin mycoses caused by Candida: 2-3 weeks. Infection of hair 1-2 months. Nail Infections: 3-6 months, if there has been no improvement can be continued up to 12 months. Also influenced by the speed of nail growth, until the infected nail is replaced by a normal nail. Parakoksidioidomikosis, histoplasmosis, coccidioidomycosis: the optimum duration of treatment 2-6 months. Side Effects clock spring repair
Oral dosage: Dyspepsia, nausea, abdominal pain and diarrhea. clock spring repair Headache, liver enzyme elevations were reversible, menstrual disorders, dizzines, paraesthesia and allergic reactions. Thrombocytopenia, alopecia, increased pressure "intracranial pressure" which is reversible clock spring repair (such papiloedema, "bulging fontanelle" in infants). Impotence is very rare. Gynaecomastia and oligospermia were reversible when the dose given is higher than the recommended therapeutic dose. Hepatitis (most likely idiosyncratic) are rare (seen in patients 1/12.000). Reversible when treatment is stopped in time. Warning and Caution: It is important to explain to patients treated for long-term about the symptoms of heart disease such as abnormal fatigue is accompanied by fever, dark urine, pale stools, or jaundice. clock spring repair Factors that increase the risk of hepatitis: women over the age of 50 years, had suffered from heart disease, are known to have intolerance to the drug, long-term administration and the administration of drugs along with drugs that affect liver function. Liver function tests performed on treatment with ketoconazole more than 2 weeks. If already diagnosed as liver disease, treatment clock spring repair should be discontinued. Adrenal function should be monitored in patients suffering from adrenal insufficiency or adrenal function were "border line" and objec stress in patients with long (basic surgical, clock spring repair intensive care, etc.). Should not be used for children under the age of 2 years. Not be given to pregnant women, except for the possibility of greater benefit than risk to the fetus. Chances are excreted in breast milk, the mother is treated with ketoconazole is not recommended for breastfeeding. Drug Interactions: Giving together with terfenadine and astemizole. The absorption of ketoconazole
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